PICCs should be flushed with 10ml saline prior to administering anything through the PICC and after each use. PICCs should be flushed using Aseptic Non Touch Technique (ANTT) at least once every seven days. A push-pause technique should be used and should end on a positive pressure. A PICC should never be flushed with a syringe smaller than 10ml as the pressure will be too great and could cause rupture.


  • Clean procedure tray/trolley
  • Non-sterile gloves and plastic apron
  • 10ml luer lock syringe
  • Filter needle
  • 10ml vial saline
  • 2% Chlorhexidine in 70% alcohol wipes

Collect equipment and place in clean procedure tray

  • Wash hands thoroughly and put on non-sterile gloves and apron
  • Draw up 10ml saline
  • Clean the hub thoroughly with 2% Chlorhexidine in 70% alcohol wipe for 30 seconds and allow to air dry for at least 30 seconds
  • Connect the 10ml luer lock syringe directly onto the bung
  • Flush the PICC using push-pause technique making sure to end on positive pressure and remove syringe
  • Dispose of equipment safely

Changing a PICC dressing

A PICC must be re-dressed at least once every seven days and this can be done using ANTT. The fixation device (Grip-Lok®/Statlock®) should be changed at least once every three weeks.


  • Clean procedure tray/trolley
  • Dressing pack
  • Chloraprep® applicator 3mls
  • Fixation device (Grip-Lok®/Stalock®)
  • Transparent semi-permeable occlusive dressing (IV3000/Tegaderm/Hydrofilm)
  • 2% Chlorhexidine in 70% alcohol wipe
  • Needle-free access device


  • Wash hands thoroughly
  • Put on Apron, open dressing pack and put dressing, Chloraprep® and needle free access device onto sterile field using ANTT
  • Remove existing dressing
  • Wash hands and put on sterile gloves
  • Clean site with Chloraprep® for 30 seconds and leave to air dry for 30 seconds
  • Note external PICC measurement (cm marking on PICC every 5cm)
  • Change fixation device if required
  • Apply dressing making sure exit site is covered
  • Remove existing needle-free access device
  • Clean hub with 2% Chlorhexidine in 70% alcohol wipe
  • Attach new needle-free access device
  • Dispose of equipment safely

If unable to flush PICC please contact the Macmillan Unit on 01935 384873

Patient information when chemo pump in situ

You’ll be sent home with a pack containing:

  • Apron
  • Gloves
  • Bung
  • Chemo Bag

In the unlikely event that the pump leaks, please contact the Macmillan Unit or phone the OOH numbers in the front of your blue book for advice and guidance.

Ref: 21-19-106
Review: 06/21